ML204是TRPC4/C5離子通道新型高效抑制劑。
Valacyclovir (hydrochloride)產品描述：Valacyclovir hydrochloride is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Target: HSV Valacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. VACV uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64 +/- 0.06 mM and 23.34 +/- 0.36 nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro . For treatment of a first episode of genital herpes, a large comparative trial has shown that valacyclovir (1 g twice a day) is as effective as acyclovir (200 mg five times a day) when given for 10 days. For treating recurrences, two trials show that valacyclovir is as effective as acyclovir (200 mg five times a day) with a treatment period of 5 days. A daily dose of 1 g of valac
公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，分別在瑞典和上海設有歐洲區(qū)子公司和亞洲區(qū)總代理，營銷網點遍及全球20多個國家地區(qū)。MCE經過多年努力已成為全球生物活性小分子領域的一流供應商， 產品涵蓋癌癥、神經科學、抗感染、表觀遺傳學等20個熱門研究領域，PI3K、MAPK等近千個細分靶點，超過4000個活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫，同時提供從毫克到千克的專業(yè)定制合成服務。
MCE 對每批產品都進行嚴格的LCMS和NMR檢驗，其產品已被全球近萬名客戶廣泛使用并發(fā)表大量文章、專利；
MCE 定期增加各領域熱門抑制劑、激動劑，不斷擴增已有化合物庫，以滿足最新的科研需求；
數千種產品在上海有充足備貨，24-48小時內送達客戶；
大量產品提供免費試用裝； 已為全球多個知名企業(yè)、院校構建各種定制型化合物庫。
產品鏈接：www.medchemexpress.cn/valacyclovir-hydrochloride.html
Purity:98%
MWt:226.3168
Formula:C15H18N2
SMILES:CC1=CC(N2CCCCC2)=NC3=CC=CC=C13
Pathway:Membrane Transporter/Ion Channel;
Mechanisms:TRP Channel;
Research Area:Neurological Disease
電話： 021-58955995
網址： www.MedChemExpress.cn
地址： 上海市浦東新區(qū)蔡倫路720號2號樓3層
Valacyclovir (hydrochloride)產品描述：Valacyclovir hydrochloride is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Target: HSV Valacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. VACV uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64 +/- 0.06 mM and 23.34 +/- 0.36 nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro . For treatment of a first episode of genital herpes, a large comparative trial has shown that valacyclovir (1 g twice a day) is as effective as acyclovir (200 mg five times a day) when given for 10 days. For treating recurrences, two trials show that valacyclovir is as effective as acyclovir (200 mg five times a day) with a treatment period of 5 days. A daily dose of 1 g of valac
公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，分別在瑞典和上海設有歐洲區(qū)子公司和亞洲區(qū)總代理，營銷網點遍及全球20多個國家地區(qū)。MCE經過多年努力已成為全球生物活性小分子領域的一流供應商， 產品涵蓋癌癥、神經科學、抗感染、表觀遺傳學等20個熱門研究領域，PI3K、MAPK等近千個細分靶點，超過4000個活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫，同時提供從毫克到千克的專業(yè)定制合成服務。
MCE 對每批產品都進行嚴格的LCMS和NMR檢驗，其產品已被全球近萬名客戶廣泛使用并發(fā)表大量文章、專利；
MCE 定期增加各領域熱門抑制劑、激動劑，不斷擴增已有化合物庫，以滿足最新的科研需求；
數千種產品在上海有充足備貨，24-48小時內送達客戶；
大量產品提供免費試用裝； 已為全球多個知名企業(yè)、院校構建各種定制型化合物庫。
產品鏈接：www.medchemexpress.cn/valacyclovir-hydrochloride.html
Purity:98%
MWt:226.3168
Formula:C15H18N2
SMILES:CC1=CC(N2CCCCC2)=NC3=CC=CC=C13
Pathway:Membrane Transporter/Ion Channel;
Mechanisms:TRP Channel;
Research Area:Neurological Disease
電話： 021-58955995
網址： www.MedChemExpress.cn
地址： 上海市浦東新區(qū)蔡倫路720號2號樓3層
110102000668（1）號